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Subtractive Cell-SELEX Selection of DNA Aptamers Binding ...

1. Introduction. Hepatocellular carcinoma (HCC) is the second most common cause of cancer-related death worldwide, estimated to be responsible for nearly 746,000 deaths in 2012 (9.1% of the total), and is a formidable public health challenge of China where 50% of the estimated 782,000 new cancer cases worldwide occurred [1, 2].In recent decades, great advancements have been achieved in the ...

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Activation of the TLR4/MyD88 signaling pathway contributes ...

HCC also appeared to be correlated with the TNM stage and tumor metastasis. In conclusion, the current results suggested that the TLR4/MyD88 signaling pathway is involved in HCC cell proliferation and metastasis via regulation of the IL-23/IL-17A axis; thus, the TLR4 /IL-23/IL-17A pathway may represent a novel therapeutic target in HCC. Introduction Human hepatocellular carcinoma (HCC) is the ...

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Variations in DEPDC5 gene and its association with chronic ...

Hepatitis C virus (HCV) is a single-stranded RNA virus that belongs to the Flaviviridae family, genus Hepacivirus. It is an enveloped and a non-cytopathic virus. Over 180 million people are infected with HCV worldwide including 94.6 million people in the Western Pacific and Southeast Asia regions, with an estimated infection rate of more than 200 million people by the year 2020

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CC-Free Downloads - The Sims 4 Catalog

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PNAS Plus: Plasma DNA tissue mapping by genome-wide ...

2015-10-06· The buffy coat DNA was obtained from a 40-y-old healthy nonpregnant woman. The placenta DNA was obtained following the delivery of a healthy female baby at 38 wk of gestation. The liver DNA was obtained from the nonneoplastic liver tissues adjacent to a hepatocellular carcinoma (HCC) at resection from a 57-y-old female subject. As can be seen in

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